However, in an Italian cohort comprising 538 CeD patients and 593 healthy controls, Romanos et al. did not find any association with the rs6441961 SNP, as previously reported by Hunt et al.15,18 Additionally, a meta-analysis study conducted in 2015 provides strong predictions that IL18RAP-rs917997, CCR3, or UQCR2P1-rs6441961 may be potential risk factors for CeD in European populations12. Here, CCR3 is linked to cranioectodermal dysplasia.