In addition, after different doses of Qiliqiangxin capsule intervention in rat models of chronic heart failure, the LDH and ROS levels in the serum of rats with HF are decreased, the activity of superoxide dismutase (SOD) is enhanced, the expression of the pro-apoptotic protein is inhibited, and the expression of B-cell lymphoma-2 (Bcl-2), p-Akt/Akt and p-GSK3β/GSK3β is upregulated. Here, AKT1 is linked to congestive heart failure.