KEGG enrichment analysis showed that downregulated pathways were enriched in regulating lipolysis as well as Peroxisome proliferator activated receptor (PPAR) signaling pathways in adipocytes, and upregulated pathways were enriched in renin secretion and hypertrophic cardiomyopathy (Fig. 3c, d). The gene discussed is PPARA; the disease is hypertrophic cardiomyopathy.