GAD1 and major depressive disorder: About neuropsychiatric profile, 17 (85%) patients exhibited moderate to severe depression in group C versus 20 (100%) of those in group D. In group C, the mean score on the PHQ-8 scale was 15.45 (IQR = 13.75–18.25) with a strong inverse correlation of PHQ-8 score and MCS component of SF12 (R = −0.96; p = 0.005) and a positive strong correlation with GAD-7 (R = 0.80; p = 0.00002).