Laboratory tests showed: Hb: 9.5g/dl, WBC: 2800/cmm, platelets: 95,000/cmm, normochromic normocytic anemia, normal liver and renal function tests, negative blood film for malaria (repeated twice), positive anti-plasmodium falciparum antibodies, high serum IgM level (200 mg/dl), normal serum IgG, negative HIV serology, negative mantoux test, and normocellular bone marrow. The gene discussed is CD40LG; the disease is malaria.