Notably, ART initiation should be delayed for 4 to 6 weeks after starting antifungal treatment for cryptococcal meningoencephalitis [24], for 4 to 6 weeks in coccidioidomycosis, especially in those with CD4 cell counts <250 cells/μL or meningitis [22], and between 2 and 8 weeks after starting antituberculous therapy, depending on the CD4 count [22]. This evidence concerns the gene CD4 and coccidioidomycosis.