Then, the combination therapy of IR‐TAM@Alb nanoparticles and RT rather than RT alone or IR‐TAM@Alb itself most effectively enhanced the generation amounts of DNA damage, amplified T cell infiltration, and enhanced T cell killing function in both bladder cancers and breast cancers, which finally almost totally inhibited local and absopal tumor growth, as well as preventing tumor metastasis (Figures 4, 5, 6). The gene discussed is ALB; the disease is urinary bladder cancer.