Treatment with BSP and culture at 4 °C resulted in the decreased fluorescence derived from IR‐TAM in 4T1 cells, implying that the internalization of IR‐TAM@Alb by tumor cells is contingent upon the presence of organic anion‐transporting polypeptides (OATPs) and the metabolic state of the cells (Figures S10 and S11, Supporting Information).[23, 24] Next, the viability of the cancer cells after TAM@Alb, IR‐68@Alb, or IR‐TAM@Alb treatment was measured using the CCK‐8 kit. The gene discussed is ALB; the disease is cancer.