GTSE1 and Familial prostate cancer: Lai et al.15found that upregulation of GTSE1 can stimulate the growth of prostate cancer cells via the SP1/FOXM1 signaling pathway, while Zhang et al.16suggested that GTSE1 induces chromosomal instability in esophageal squamous cell carcinoma cells and inhibits cell apoptosis through the ROS/JNK signaling pathway.