In our secondary analyses, comparing PwMS/anxiety to healthy controls, we found a 1‐SD GAD‐2 PGS increase was associated with similar odds of comorbid moderate anxiety to that of the primary (OR per 1‐SD increase in GAD‐2 PGS: 1.45, 95% CI: 1.05–1.98, Table S4). This evidence concerns the gene GAD2 and Anxiety.