AIP and autoimmune pancreatitis: Multivariable regression analysis showed that the risk of CMD in class2 was 1.31 times that of class1, and in class3, it was 1.34 times; 4) Persistently high AIP levels were independent predictors of CMM risk in the middle-aged and elderly; 5) The relationship between changes in AIP and cumulative AIP with CMD was more significant in men than in women, with a significant interaction effect between cumulative AIP and gender (p for interaction = 0.042); 6) The dose-response curve between cumulative AIP and CMD showed a linear relationship in male.