Reactive microglial load (CD68-positive) was significantly higher in mixed DLB + AD cases compared to pure DLB cases in the amygdala and PHG (p < 0.001 and p = 0.004 respectively), in pure AD cases when compared to pure DLB cases in the CA1, CA2, the subiculum and amygdala (p = 0.004, p = 0.028, p = 0.002, p < 0.001, respectively) and in pure AD cases when compared to mixed DLB + AD cases in the CA2 and subiculum (p = 0.01 and p = 0.014 respectively). This evidence concerns the gene CD68 and Lewy body dementia.