Conflicting results on activated CD68-positive or HLA-DR-positive microglia in DLB phenotypes have been reported previously, in which some studies found an increase in the amygdala, hippocampus, transentorhinal cortex and TC compared to controls [26, 27, 29, 30], while others did not report an increase in the hippocampus or neocortex [31, 32]. This evidence concerns the gene CD68 and Lewy body dementia.