Bisulfite sequencing [28] of chromosomal DNA from lymphoma cell lines and immortalized IM9 B cells confirmed that these NMT2 loci were methylated (dark spheres) in DOHH2 and WSU-DLCL2 lymphoma cells, but not in BL2, benign IM9 cells, and lymphocytes (open circles) (Fig. 2C). Here, NMT2 is linked to lymphoma.