Aggregation methylation at the NMT2 locus in tumors and normal tissues showed increased methylation in breast, colon, kidney, and lung tumors compared to that in the associated normal tissues (Additional file 1: Fig. S9B–E) and was significantly inversely correlated with its expression in DLBCL (Fig. 2B). The gene discussed is NMT2; the disease is diffuse large B-cell lymphoma.