Also, the antitumor effects of this nanoparticle were investigated in the body of mice with glioblastoma, the findings of which indicated that U2-AuNP inhibits the proliferation and invasion of U87-EGFRvIII cell lines and EGFR-related pathway, preventing DNA damage repair in GBM cells [126]. This evidence concerns the gene EGFR and glioblastoma.