Among the 122 patients who underwent NGS, the commonly mutated genes in MDS/MPN-SF3B1-T included SF3B1 (93.4%), JAK2 (32.8%), TET2 (29.5%), DNMT3A (21.3%), ASXL1 (17.2%), TP53 (8.2%), MPL (6.6%), SETBP1 (6.6%), and SRSF2 (4.9%) (Fig. 1B and Supplementary Table S3). This evidence concerns the gene DNMT3A and myeloproliferative neoplasm.