Next, the results of KEGG pathway analysis and GSEA analysis showed that some upregulated pathways in Blood group compared with Control group (Fig. 2n, o) were downregulated in Blood+sc group, mainly related to steatosis, fat metabolism and apoptosis, such as PPAR signaling pathway, biosynthesis of unsaturated fatty acid, oxidative phosphorylation and p53 signaling pathway (Fig. 7g, i), suggesting the recovery effects in Blood+sc group. This evidence concerns the gene TP53 and steatosis.