MYC and Miyoshi myopathy: Consistently, we confirmed targeting of the somatic mutation process to the Vk*MYC transgene causing reversion of the stop codon that controls MYC translation in 71 out of 84 unique MM analyzed by mRNA, associated with an average of 4.5% somatic hypermutation at the immunoglobulin loci7, while the remaining cases without reversion of the stop codon have less than 2% (Supplementary Data 18, 19).