After removing the Vk*MYC transgene insertion breakpoints and the deletions associated with VDJ and class switch recombination within immunoglobulin genes (Ig), we observed a median of 8.5 (range 0–351) SVs per tumor, significantly lower compared to that observed in human MM (16, range 0–351; p = 0.00017 using Wilcoxon test). The gene discussed is MYC; the disease is Miyoshi myopathy.