CD8A and type 1 diabetes mellitus: Importantly, when we combined all the samples from the three autoantibody groups (all samples group) and analyzed them together, we found no differences in the proportions of these cell types between the children developing type 1 diabetes and controls at FDR ≤ 0.05 (Supplementary Table 2), with the exception of a decreased proportion of CD8+ T cells in cases compared to the controls associated with disease progression (FDR = 0.008, Fig. 2c).