CCL5 and CCL18 upregulate various glycolysis-promoting factors, including hexokinase 2 (HK2), phosphoglycerate kinase 1 (PGK1), glucose-6-phosphate dehydrogenase (G6PD), and pyruvate kinase, further facilitating tumor progression [14, 16]. The gene discussed is G6PD; the disease is neoplasm.