Conditional logistic regression analysis revealed that BMI, hypertension, traditional lipid parameters (TC and LDL-C), and non-traditional lipid parameters (nonHDL-C, APOB, APOE, ATH index, AI, CRI-I, CRI-II, and LCI) were risk factors for the onset of SSNHL (Fig. 1, Model 1). This evidence concerns the gene APOE and hypertensive disorder.