Pairwise comparison of AD to controls outlined a large fold increase in M89 “Matrisome/Heparin‐binding” proteins, such as SMOC1, MDK, C4B, SFRP1, and NTN1 with high specificity even as these proteins were not differentially expressed in the PSP versus control comparison. Here, SFRP1 is linked to supranuclear palsy, progressive, 1.