METTL3 and colonic neoplasm: For human glioblastoma U251 cells (Figure8A; Figure S10A,B, Supporting Information) and human colon cancer HCT116 cells (Figure 8B; Figure S10C,D, Supporting Information), the results strongly supported that the m6A writers METTL3 and METTL14 were down‐regulated upon the addition of bile acids, especially at high concentrations.