To potentially explain how high levels of microdystrophin leads to cardiomyopathy, we sought to determine if microdystrophin displaces utrophin from the cardiomyocyte membrane, as it is possible that strong overexpression of microdystrophin may phenocopy utrophin ablation via replacement with a truncated, and potentially less functional, dystrophin molecule. The gene discussed is UTRN; the disease is cardiomyopathy.