Human Parkinson disease protein 7 (PARK7),also known as DJ-1,is a small (∼20 kDa) multifunctional protein,1,2 which is associated with various types of cancer and Parkinson’sdisease.3−5 Throughout the years, PARK7 has been found to playa major role in protecting cells from stress conditions, especiallyoxidative stress, via its enzymatic and nonenzymatic functions.6 The key element for PARK7 functioning is thehighly conserved cysteine residue at position 106. This evidence concerns the gene PARK7 and cancer.