IL1B and neoplasm: The main mechanism by which CRS occurs is the disruption of the balance between pro‐ and anti‐inflammatory in the body, where monocytes are activated and secrete cytokines such as IL‐6 and IL‐1 in response to the interaction of CAR‐T cells and tumour cells, followed by peripheral molecules that initiate the activation of endothelial cells and initiate pro‐inflammatory pathways, thus disrupting the balance between pro‐ and anti‐inflammatory.103