Ghorbaniet al. (2014) found that eating walnuts as part of adiabetic diet reduced serum glucose levels and improved sex hormone secretion inmale diabetics. Furthermore, diabetes has been demonstrated to affect the malehypothalamus-pituitary axis of the gonad, resulting in a considerable drop intestosterone (Maneesh et al.,2006). Changes in androgenic hormones like luteinizing hormone (LH) andtestosterone levels have also been associated with diabetes (Arikawe et al., 2012). Here, PLOD1 is linked to diabetes mellitus.