Our findings indicated that female gender (HR = 0.781; 95% CI: 0.707–0.863; P < 0.01), Black race (HR = 0.812; 95% CI: 0.679–0.971; P = 0.022), age under 65 years (HR = 0.654; 95% CI: 0.590–0.726; P < 0.01), a negative/normal CEA level (HR = 0.816; 95% CI: 0.723–0.920; P = 0.001), and radiotherapy (HR = 0.809; 95% CI: 0.654–0.924; P = 0.041) were associated with a decreased likelihood of recurrence among patients with stage I CRC (Figure 5). This evidence concerns the gene CEACAM5 and colorectal carcinoma.