The findings revealed that several factors were independently associated with the survival of patients with recurrent stage I CRC: age (<65 vs. ≥65 years: HR = 0.462; 95% CI: 0.3379–0.564; P < 0.001), race (Black vs. White: HR = 1.435; 95% CI: 1.121–1.837, P = 0.004; other vs. White: HR = 0.705; 95% CI: 0.504–0.985, P = 0.041), T stage (T1 vs. T2: HR = 0.82; 95% CI: 0.690–0.969, P = 0.020), and CEA status (negative/normal vs. positive/elevated: HR = 0.641; 95% CI: 0.537–0.766; P < 0.0001) (Figure 4). The gene discussed is CEACAM5; the disease is colorectal carcinoma.