Correlations were examined between pappalysins, stanniocalcins, and markers of the growth axis (IGFs, IGFBPs), beta-cell reserve (C-peptide), initial presentation (ketoacidosis, hyperglycemia), HbA1c, exogenous insulin dose, auxology (height, growth velocity, weight, BMI), and nutrition (prealbumin, transferrin, T3T, and retinol). The gene discussed is INS; the disease is Hyperglycemia.