In Fig. 3A, ADNC A and B scores, the regression line and 95% confidence intervals are plotted in MSA and non-MSA cases with available APOE genotypes (n = 143), revealing a strong correlation between ADNC A and B scores (r = 0.71, P < 0.001), with ADNC A3B1 above the upper limit of the 95% confidence interval. Here, APOE is linked to multiple system atrophy.