TUBA1A variants were found as the most common cause of microlissencephalies in foetuses.22 The missense variant p.(Asn101Lys) in TUBA1A in FINLIS22-3 was located in the same codon as previously described in a foetus with p.(Asn101Ser) that showed a poorly differentiated cortical plate22 and in a person with microlissencephaly.21 FINLIS4-3 with a pathogenic missense variant p.(Pro259Leu) in TUBB2B had bilateral perisylvian and perirolandic PMG. This evidence concerns the gene TUBA1A and microlissencephaly.