INS and Insulin resistance: In addition to other insulin resistance assessment tools that do not require fasting insulin levels, including the product of glucose and triglycerides (TyG index), the product of glucose, triglycerides, and body mass index (TyG-BMI index), and the ratio of triglycerides divided by high density lipoprotein-cholesterol (TG/HDL-C ratio) (12–14), METS-IR emerges as an innovative tool for estimating insulin resistance.