SOX10 and Waardenburg syndrome type 2: Given that the SOX10 gene is involved in the molecular etiology of the five WS2 patients investigated by TGS, we performed a targeted mutational screening by Sanger sequencing of exon 2 of the SOX10 gene in two cases belonging to the same family DF592-1 (mother) and DF592-2 (daughter) with WS2.