The results of this retrospective cohort have found that the incidence of CAL in children with Kawasaki disease is 18.38%, and being male, aged ≤2 years, a duration of fever ≥10 days, Hb ≤105 g/L, and CRP ≥100 mg/L are the risk factors of CAL in children with Kawasaki disease. This evidence concerns the gene CRP and Kawasaki disease.