Notably, while DAT SPECT can help differentiate parkinsonian syndromes from other conditions, it does not distinguish among specific parkinsonian syndromes (such as PD, PSP, MSA, CBD, or DLB), and a holistic diagnostic approach should be employed to differentiate between them based on clinical features and additional diagnostic tests. The gene discussed is SLC6A3; the disease is supranuclear palsy, progressive, 1.