In sum, these data unveil that HLF downregulation was correlated with better prognosis of BLCA and READ patients and poor OS outcome of patients with CESC, HNSC, KIRC, KIRP, LGG, LIHC, LUAD, MESO, PAAD, SARC, and UVM. The gene discussed is HLF; the disease is cervical squamous cell carcinoma.