BRCA1 and breast carcinoma: In addition to the C1qBP gene, chromosome 17 (Figure 1), is also home to some of the most powerful oncogenes, including HER2, TOP2A, TAU, as well as to tumor suppressor genes including BRCA-1, p53, and HIC-1, that are known to be associated with several types of cancer, including breast cancer (BRCA-1).