Thus, we next sought to directly compare the effects of IFN-γ on PD-L1 levels across tumor cell types, including the mouse Pan02 pancreatic cancer cells, mouse 4T1 mammary tumor cells, DLM8 mouse osteosarcoma cells, and a human U251 glioblastoma cell line (Figure 6E). The gene discussed is CD274; the disease is pancreatic neoplasm.