LGALS3 and adult-onset Still disease: Significant increases in the serum concentrations of Gal-3 and M2BPGi were found in the serum of patients with AOSD compared with those with RA (p <0.001 for both Gal-3 and M2BPGi) as well as with healthy participants (p <0.001 for both Gal-3 and M2BPGi).