Matsuo H, Kohno K, Niihara H, et al. Specific IgE determination to epitope peptides of ω-5 gliadin and high molecular weight glutenin subunit is a useful tool for diagnosis of wheat-dependent exercise-induced anaphylaxis [J]. J Immunol, 2005, 175: 8116-8122. The gene discussed is IGHE; the disease is anaphylaxis.