Following screening based on the inclusion and exclusion criteria, 15 RA patients (12 females and 3 males) with an average age of 55.13 ± 17.88 years and an average DAS28 score of 5.5 ± 1.35 were included in the control group, 26 recruiters (15 females and 11 males) with an average age of 55.65 ± 11.3 years and an average DAS28 score of 5.31 ± 1.18 were included in the IL-2 group, and 9 subjects (8 females and 1 male) with an average age of 45.67 ± 12.33 years and an average DAS28 score of 5.68 ± 1.02 were included in the IL-2+TCZ group. Here, IL2 is linked to rheumatoid arthritis.