The probability of uncontrolled asthma when treated with anti-IL5/5R therapy was reduced from 0.42 (95% CI: 0.36, 0.48) at BEC of 50 cells/μL to 0.24 (95% CI: 0.19, 0.30) at BEC 1000 cells/μL, but remained relatively constant in the anti-IgE group, ranging from 0.35 to 0.32 over the same BEC range (Figure 1B; Supplementary Table 6A). Here, IL5 is linked to asthma.