Finally, Jansen et al. [11] identified 29 genome-wide significant genetic variants corresponding to 29 AD susceptibility loci, including nine novel loci (AC074212.3, KAT8, CLNK, ALPK2, APH1B, CNTNAP2, ADAM10, ADAMTS4 and HESX1). The gene discussed is APH1B; the disease is Alzheimer disease.