SORL1 and Alzheimer disease: Importantly, GWAS+GWAX2022a, but not GWAS+GWAX2021, identified the most significant signals for the majority of the 82 loci and especially for 13 of these 14 loci (excluding SORL1) that were repeated among all the 9 AD GWAS and GWAS+GWAX datasets (Table 2).