PIK3CA and neoplasm: Since we observed a significant increase in the lymphoid fraction pre‐ versus posttreatment in the PI3K/mTORi‐ and PI3K/mTORi+PD‐1i‐treated tumours, we further analysed the TILs and, based on marker gene expression, identified NK‐cell, CD4+ and CD8+ T‐cell populations (Figure 3A and B).