In a 2022 case report by Yang et al. [10], a neonatal patient with midface retraction and developmental delay was diagnosed with “non-classical” SGS based on the absence of hydronephrosis and skeletal abnormalities at birth, and the presence of a SETBP1 gene variant, S869G, according to the Lehman diagnostic criteria. This evidence concerns the gene SETBP1 and hydronephrosis.