CTBP1 and cancer: Surprisingly, while EGCG and EE promoted Golgi fission fragmentation (presumably inducing the monomeric fission-prone conformation of CtBP1/BARS) (Fig. 1C), Comp.11 induces Golgi membrane tubulation in all the cancer cell lines (Fig. 1C and 1E, Supplementary Fig. 1B and Supplementary Fig. 2) that resembles a membrane fission defect seen upon inhibition of CtBP1/BARS monomerization [35, 64, 68].