Our analyses of the correlations of membranous/cytoplasmic/nuclear GSDMB expression with CD3+/CD4+/CD8+ T lymphocytes, CD20+ B lymphocytes, CD68+ macrophages, and S100A8+ immune cells showed that membranous or nuclear GSDMB expression was positively correlated with S100A8+ immune cells in the TIF, whereas nuclear GSDMB was linked to a higher number of CD68+ macrophages in the entire tumor. The gene discussed is CD4; the disease is neoplasm.