Western blotting analysis was performed In MCF-7, MDA-MB-231, T-47D breast cancer, and MCF10A breast normal cell lines, to check protein expression of MBD1, MBD2, MeCP2, BRCA1, BRCA2, p16, and β-actin genes in relation to resveratrol treatment. This evidence concerns the gene MBD2 and breast cancer.