ESR1 and breast cancer: In ER+, PR+ breast cancer cells, BRCA1 was down-regulated and MBD1, MBD2, MeCP2, BRCA2, & p16 was up-regulated, but in Triple-negative breast cancer cells, MBD2 was down-regulated and MBD1, MeCP2, BRCA1, BRCA2, & p16 gene was elevated following treatment with resveratrol.