Moreover, Relma and Relmb have been found to be highly expressed in bleomycin‐induced pulmonary fibrosis and to participate in the development of this condition, while the inhibition of Relma or Relmb reduces the expression of ECM remodeling genes, such as Col1a1, Col3a1, and α‐smooth muscle actin, thereby inhibiting the progression of pulmonary fibrosis [30, 31, 32]. The gene discussed is RETNLB; the disease is pulmonary fibrosis.