Comparative analysis with key clinical features outlined in Table 2 revealed a positive correlation between the immunointensity of FCGBP and lymph node metastases before CRT (p = 0.001), tumor invasion, and positive lymph node metastases after CRT (both p < 0.001), vascular invasion (p = 0.001), perineural invasion (p = 0.041), and a lower tumor regression grade (p < 0.001). The gene discussed is FCGBP; the disease is metastatic malignant neoplasm in the lymph nodes.