In a preliminary experiment following up on the inhibition of p53 activity by SARS-CoV-2 spike protein, no cell cycle arrest was detected at G1, S or G2-M phases in cancer cells transfected with pcDNA3.1-SARS2-spike, as compared to the pcDNA3.1 transfection control (Figure 2C). The gene discussed is SARS2; the disease is cancer.