It was observed by HE staining that there was obvious apoptosis of tumor tissues, a large number of cells died, the tissue structures mostly disappeared, karyopyknosis was found, a large number of apoptotic cells were dispersed around the tissues, and the cells lost their normal morphology in the pGCsiRNA-VEGF group as compared to the mock group and the si-scramble group, suggesting significant efficacy in the pGCsiRNA-VEGF group. This evidence concerns the gene VEGFA and neoplasm.